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Search Results for " tissue factor "
Targets Recommended: Others

17

抑制剂 & 化合物

3

天然产物

2

化合物库

89

重组蛋白

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Cat. No. Product Name
L8500 HIF-1化合物库

1336 compounds
1336 个HIF-1相关小分子的独特集合,可用于缺血性疾病、癌症等相关领域的药物开发和药理研究;
L6750 活血化瘀中药单体库

580 compounds
580种来源于常见活血化瘀中药的单体化合物,是药物开发、药理研究等领域的有效工具。

化合物库

HIF-1化合物库
Cat.No: L8500
Compounds: 1336
活血化瘀中药单体库
Cat.No: L6750
Compounds: 580
Cat. No. Product Name Target Signaling Pathways
T4502 BISMUTH SUBGALLATE

次没食子酸铋,Dermatol Puder,Bismuth Gallate

Others Others
Bismuth subgallate (Dermatol Puder) 是一种止血剂,可作用于凝血因子 XII ,促使凝血级联的激活,改善纤维蛋白凝块的早期形成。
T35343 MTI-31

MTI-31,LXI-15029

mTOR PI3K/Akt/mTOR signaling
MTI-31 (LXI-15029) 是口服有效的,高度选择性的mTORC1和mTORC2抑制剂,对 mTOR 的Kd 为 0.20 nM,IC50为 39 nM。MTI-31可用于乳腺癌的研究。
T77372 Tisotumab

1E10,1.00E+10

Others Others
Tisotumab (Anti-Human F3 Recombinant Antibody) 是一种针对组织因子 (TF) 的人 IgG1 单克隆抗体。Tisotumab 参与抗体偶联药物,可用于研究癌症。
T76761 Olaratumab

LY3012207,IMC-3G3

PDGFR Angiogenesis; Tyrosine Kinase/Adaptors
Olaratumab(IMC-3G3) 是一种人源抗血小板衍生生长因子受体α (PDGFRα)单克隆 IgG1 抗体,具有抗肿瘤作用,可用于研究晚期软组织肉瘤。
T15577 Indobufen

Ibustrin,吲哚布芬

COX Immunology/Inflammation; Neuroscience
Indobufen (Ibustrin) 是一种血小板聚集抑制剂,是下调单核细胞中的组织因子,可逆抑制血小板环氧合酶 (Cox) 的活性和血栓素 A2 (TxA2) 的合成。
T21632 Myoseverin

Others; Microtubule Associated Cytoskeletal Signaling; Others
Myoseverina 是多核肌管可逆分裂成单核片段的诱导剂,影响多种生长因子、免疫调节、细胞外基质重塑和应激反应基因的表达,与伤口愈合和组织再生相关通路的激活一致。
T3469 PCI-27483

PCI27483

Others Others
PCI-27483 是一种FVIIa/tissue factor 抑制剂,具有抗肿瘤的作用。
T28222 5-Hydroxy-1-methylhydantoin

HD-003,HD003,5-羟基-1-甲基咪唑啉-2,4-二酮,NZ419,NZ-419,HD 003,NZ 419

Bradykinin Receptor GPCR/G Protein
5-Hydroxy-1-methylhydantoin (HD-003) 是一种可能用于治疗肾衰竭的抗氧化剂。它是肌酐代谢物,是一种羟基自由基清除剂,此前已显示通过抑制大鼠慢性肾病的进展来提供肾脏保护。 它是一种新型抗氧化药物,可完全抑制 B2-激肽受体(B2KR) 对 VSMC 中高葡萄糖 (25 mM) 刺激的反应,并且还显示可减弱 BK 对 VSMC 重塑的影响。它抑制 BK 诱导的 MAPK 磷酸化增加并减弱 VSMC 中结缔组织生长因子 (CTGF) 蛋白水平的增加。这些研究结果表明,它可能通过其抗氧化特性赋予血管保护免受高葡萄糖浓度和 BK 刺激以改善血管损伤和重塑。
T29501 A 68828

A68828,A-68828

A 68828 is an analog of the atrial natrium factor. It improves kidney function and reduces tissue damage.
T81854 Marstacimab

PF-06741086

Marstacimab (PF-06741086),一种针对组织因子通路抑制剂(TFPI)的单克隆抗体,适用于血友病研究。
T69456 Melagatran monohydrate

Melagatran monohydrate is a thrombin inhibitor. Melagatran prevents tissue factor expression in human platelet-monocyte heterotypic complexes. Melagatran reduces advanced atherosclerotic lesion size and may promote plaque stability in apolipoprotein E-deficient mice.
T76921 Befovacimab

Befovacimab (BAY 1093884),一种全人源单克隆IgG2抗体,特异性结合于组织因子通路抑制剂(TFPI),适用于血友病A/B的研究。
T77881 Tisotumab vedotin

Tisotumab vedotin是一种针对组织因子(tissue factor, TF)的抗体-药物偶联物(ADC),由全人源单克隆抗体(TF-011)与Monomethyl Auristatin E (MMAE)耦合而成,具有显著抗肿瘤活性,适用于晚期或转移性实体瘤的治疗研究。
T75152 ARC19499

ARC19499 是一种核酸适配体, 与组织因子通路抑制剂(TFPI)特异性结合,阻断 TFPI 对factor Xa 和 TF/factor VIIa 复合物的抑制作用。ARC19499 纠正血友病A 和B 血浆中的凝血酶生成,并恢复凝血。
T76804 FG-3019

FG-3019 (Pamrevlumab)为重组人源化抗体,特异性结合于结缔组织生长因子(CTGF)。适用于特发性肺纤维化(IPF)研究领域。
T68302 KD3010 tosylate

KD-3010 is a peroxisome proliferator-activated receptor delta agonist potentially for the treatment of diabetes and obesity. KD-3010 dramatically ameliorates liver injury induced by carbon tetrachloride (CCl(4)) injections. Deposition of extracellular matrix proteins was lower in the KD3010-treated group than in the vehicle- or GW501516-treated group. Interestingly, profibrogenic connective tissue growth factor was induced significantly by GW501516, but not by KD-3010, following CCl(4) treatmen...
T37651 5(S),6(R)-11-trans DiHETE

5(S),6(R)-11-trans DiHETE is a C-11 double bond isomer of 5(S),6(R)-DiHETE that is formed by the enzymatic isomerization of 5(S),6(R)-DiHETE by a membrane bound factor. 5(S),6(R)-11-trans DiHETE has been found in rat kidney homogenates and is potentially formed by the epoxide hydrolase pathway in this tissue. The isomerase activity responsible for the conversion of leukotriene B4 (LTB4) to 6-trans LTB4 in rat kidney homogenates has also been implicated in its formation. 5(S),6(R)-11-trans DiHETE...

化合物

BISMUTH SUBGALLATE
Cat.No: T4502
Synonym: 次没食子酸铋,Dermatol Puder,Bismuth Gallate
Target: Others
MTI-31
Cat.No: T35343
Synonym: MTI-31,LXI-15029
Target: mTOR
Tisotumab
Cat.No: T77372
Synonym: 1E10,1.00E+10
Target: Others
Olaratumab
Cat.No: T76761
Synonym: LY3012207,IMC-3G3
Target: PDGFR
Indobufen
Cat.No: T15577
Synonym: Ibustrin,吲哚布芬
Target: COX
Myoseverin
Cat.No: T21632
Synonym:
Target: Others, Microtubule Associated
PCI-27483
Cat.No: T3469
Synonym: PCI27483
Target: Others
5-Hydroxy-1-methylhydantoin
Cat.No: T28222
Synonym: HD-003,HD003,5-羟基-1-甲基咪唑啉-2,4-二酮,NZ419,NZ-419,HD 003,NZ 419
Target: Bradykinin Receptor
A 68828
Cat.No: T29501
Synonym: A68828,A-68828
Target:
Marstacimab
Cat.No: T81854
Synonym: PF-06741086
Target:
Melagatran monohydrate
Cat.No: T69456
Synonym:
Target:
Befovacimab
Cat.No: T76921
Synonym:
Target:
Tisotumab vedotin
Cat.No: T77881
Synonym:
Target:
ARC19499
Cat.No: T75152
Synonym:
Target:
FG-3019
Cat.No: T76804
Synonym:
Target:
KD3010 tosylate
Cat.No: T68302
Synonym:
Target:
5(S),6(R)-11-trans DiHETE
Cat.No: T37651
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T2S0504 Ilexoside D

Others Others
Ilexoside D has ant-allergic, and anti-coagulant activities, it shows anti-tissue factor activity as well as the antithrombotic activity.
T2S2264 Linalool

Linalol,(±)-Linalool,Phantol,沉香醇

Apoptosis; IL Receptor; TNF; Endogenous Metabolite; iGluR Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience
Linalool (Linalol) 是存在芫荽等植物中的单萜类天然产物,是竞争性NMDA 受体拮抗剂,具有抗肿瘤和抗心脏毒性的作用。它通过激活 Nrf2 诱导抗氧化防御和通过抑制 NF-κB 减少炎症反应来保护其免受 LPS/GalN 诱导的肝损伤,具有镇痛、抗菌和抗炎的特性。
T41139 Echinocystic acid 28-O-β-D-glucoside

Echinocystic acid 28-O-β-D-glucoside is a metabolite resulting from the microbial oxidation and glucosidation of Echinocystic acid. It exhibits inhibitory activity towards the tissue factor pathway, with an IC50 value measured at 10.61 nM.

天然产物

Ilexoside D
Cat.No: T2S0504
Synonym:
Target: Others
Linalool
Cat.No: T2S2264
Synonym: Linalol,(±)-Linalool,Phantol,沉香醇
Target: Apoptosis, IL Receptor, TNF, Endogenous Metabolite, iGluR
Echinocystic acid 28-O-β-D-glucoside
Cat.No: T41139
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-05094 Tissue Factor Protein, Cynomolgus, Recombinant (His)

coagulation factor III (thromboplastin, tissue<...

Cynomolgus HEK293 Cells
Tissue Factor Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.4 kDa and the accession number is XP_005542723.1.
TMPY-02530 Tissue Factor Protein, Human, Recombinant (His)

CD142,coagulation factor III (thromboplastin, t...

Human HEK293 Cells
Tissue Factor Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P13726.
TMPY-02318 Tissue Factor Protein, Rabbit, Recombinant (His)

coagulation factor III (thromboplastin, tissue<...

Rabbit HEK293 Cells
Tissue Factor Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.4 kDa and the accession number is P24055.
TMPY-03209 Tissue Factor Protein, Rat, Recombinant (His)

coagulation factor III (thromboplastin, tissue<...

Rat HEK293 Cells
Tissue Factor Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.2 kDa and the accession number is Q66HI4.
TMPY-02537 Tissue Factor Protein, Human, Recombinant (hFc)

coagulation factor III,coagulation factor ...

Human HEK293 Cells
Tissue Factor Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.8 kDa and the accession number is P13726.
TMPK-00993 Coagulation Factor III/Tissue Factor Protein, Canine, Recombinant (His)

Thromboplastin,CD142,TF,FLJ17960,TFA,F3,Coagulation Fact...

Canine HEK293 Cells
Tissue factor (also named Coagulation Factor III) is a cell surface glycoprotein responsible for initiating the extrinsic pathway of coagulation.Tissue factor is the primary cellular initiator of blood coagulation via interaction with coagulation factor VII. Aberrant expression of tissue factor is responsible for thrombosis during septic shock, atherosclerosis and cancer.
TMPY-01325 Tissue Factor Protein, Mouse, Recombinant (His)

Cf-3,AA409063,CD142,coagulation factor III (thrombo...

Mouse HEK293 Cells
Tissue Factor Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is A0A0R4J088.
TMPY-06957 Tissue Factor Protein, Human, Recombinant (hFc & Avi), Biotinylated

TFA,coagulation factor 3,coagulation factor

Human HEK293 Cells
Tissue Factor Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 53.34 kDa and the accession number is P13726.
TMPY-05083 Tissue Factor Protein, Human, Recombinant (aa 1-295, His)

coagulation factor 3,TF,TFA,coagulation factor<...

Human Baculovirus Insect Cells
Tissue Factor Protein, Human, Recombinant (aa 1-295, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 31 kDa and the accession number is P13726-1.
TMPY-01030 TFPI Protein, Human, Recombinant (His)

TFPI1,tissue factor pathway inhibitor (lip...

Human HEK293 Cells
TFPI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.6 kDa and the accession number is P10646-1.
TMPJ-01163 CTGF/CCN2 Protein, Human, Recombinant (HEK293, His)

CTGF,Connective tissue growth factor

Human HEK293 Cells
Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CYR61/CTGF/NOV) family of secreted matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF has various biological functions, including cell adhesion, migration, proliferation, differentiation, and ECM production, and participates in the development of many organs under normal physio...
TMPY-02859 TFPI2 Protein, Mouse, Recombinant (hFc)

PP5/TFPI-2,AV000670,tissue factor pathway ...

Mouse HEK293 Cells
TFPI2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.4 kDa and the accession number is O35536.
TMPY-02329 TFPI2 Protein, Mouse, Recombinant (His)

tissue factor pathway inhibitor 2,PP5/TFPI...

Mouse HEK293 Cells
TFPI2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.8 kDa and the accession number is O35536.
TMPY-01004 TFPI2 Protein, Human, Recombinant (His)

REF1,PP5,tissue factor pathway inhibitor 2...

Human HEK293 Cells
TFPI2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.2 kDa and the accession number is P48307-1.
TMPY-05179 TFPI Protein, Human, Recombinant (His), Biotinylated

TFI,TFPI1,EPI,LACI,tissue factor pathway i...

Human HEK293 Cells
TFPI Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.6 kDa and the accession number is P10646-1.
TMPY-00928 TFPI Protein, Mouse, Recombinant (His)

AW552122,A630013F22Rik,tissue factor pathw...

Mouse HEK293 Cells
TFPI Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is O54819-1.
TMPJ-01162 CTGF/CCN2 Protein, Human, Recombinant (hFc)

IGFBP8,Connective tissue growth factor,Hyp...

Human HEK293 Cells
CTGF/CCN2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 67-81 KDa and the accession number is Q5M8T4.
TMPJ-01161 CTGF/CCN2 Protein, Human, Recombinant

IGFBP-8,CCN family member 2,IBP-8,Connective tissue...

Human HEK293 Cells
CTGF/CCN2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16-25 KDa and the accession number is Q5M8T4.
TMPH-02568 CTGF/CCN2 Protein, Mouse, Recombinant (GST)

betaIG-M2,Connective tissue growth factor,...

Mouse E. coli
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
TMPH-01069 CTGF/CCN2 Protein, Human, Recombinant (His)

Hypertrophic chondrocyte-specific protein 24,CCN family memb...

Human E. coli
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. CTGF/CCN2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 15.1 kDa and...
TMPJ-00014 Resistin Protein, Human, Recombinant (His)

Resistin,C/EBP-epsilon-regulated myeloid-specific secreted c...

Human E. coli
Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. The length of the resistin pre-peptide in human is 108 amino acid residues and in the mouse and rat it is 114 aa; the molecular weight is ~12.5 kDa. Resistin is a cytokine whose physiologic role has been the subject of much controversy regarding its involvement wit...
TMPJ-00090 FGF-9 Protein, Human, Recombinant

Fibroblast Growth Factor 9,Heparin-Binding Growth <...

Human E. coli
Fibroblast Growth Factor 9 (FGF-9) belongs to the Fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-9 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. In addition, FGF-9 may have a role in glial c...
TMPY-03958 TGF alpha Protein, Human, Recombinant

transforming growth factor α,转化生长因子,transforming gr...

Human E. coli
The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared to adjacent normal tissue and high TGFA gene expression strongly correlated with poor survival in patients with lung adenocarcinoma, and miR-374a suppresses lung adenocarcinoma cell proliferation and invasion via targeting TGFA gene expression. Transforming growth factor alpha (...
TMPY-01075 Von Willebrand Factor/vWF Protein, Human, Recombinant (His)

von Willebrand factor,VWD,F8VWF

Human CHO Cells
Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury. From studies it appears that VWF protein uncoils under these circumstances, decelerating passing platelets. VWF protein is deficient or defective in von Willebrand disease (VWD) and is involved in a large number of other diseases, including thrombosis, thrombotic thr...
TMPY-00117 FGF-16 Protein, Human, Cynomolgus, Recombinant

fibroblast growth factor 16

Human,Cynomolgus Baculovirus Insect Cells
Fibroblast growth factor 16 (FGF16) is preferentially expressed in the heart after birth, suggesting its regulation is associated with tissue-specific chromatin remodeling and DNA-protein interactions. Mutation of the MEF2 site resulted in a blunting of FGF16 promoter activity in transfected neonatal rat cardiac myocytes, that chromatin remodeling and MEF2 binding in the FGF16 promoter contribute to expression in the postnatal heart. FGF16 involvement in the fine tuning of the human skeleton of ...
TMPY-03382 FGF-6 Protein, Human, Recombinant

HBGF-6,HST2,fibroblast growth factor 6

Human E. coli
FGF6, also known as FGF-6, belongs to the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF6 plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis. It is also required for normal muscle regeneration. FGF6 gene d...
TMPJ-00842 FGF-2 Protein, Rat, Recombinant

bFGF,Heparin-Binding Growth Factor 2,FGFB,Fibroblas...

Rat E. coli
FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. They act on several cell types to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects, and tissue repair. FGF-basic is a non-glycosylated heparin binding g...
TMPY-03104 FGF-17 Protein, Human, Recombinant

fibroblast growth factor 17,HH20,FGF-13,FGF-17

Human E. coli
FGF-13, also known as FGF17, belongs to the fibroblast growth factor (FGF) family. Members of this family show broad mitogenic and cell survival activities, and play a role in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-13 is preferentially expressed in the embryonic brain. It interacts with FGFR3 and FGFR4. FGF-13 plays an important role in the regulation of embryonic development and as signaling mol...
TMPY-01101 Coagulation factor X/F10 Protein, Human, Recombinant (His)

FXA,FX,coagulation factor X,coagulation factor<...

Human Baculovirus Insect Cells
Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the coagulation cascade and blood clotting, as the first enzyme in the common pathway of thrombus formation. Factor X deficiency is one of the rarest of the inherited coagulation disorders. FX deficiency among the most severe of the rare coagulation defects, typically including hema...
TMPY-01061 FGF-10 Protein, Human, Recombinant

fibroblast growth factor 10,KGF2

Human E. coli
Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF10 exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. FGF10 pla...
TMPY-02907 FGF-19 Protein, Human, Recombinant

fibroblast growth factor 19,FGF19

Human E. coli
FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF19 interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by KL, KLB and heparan sulfate glycosaminoglyca...
TMPJ-00994 LTBR Protein, Mouse, Recombinant (hFc)

Tnfcr,Lymphotoxin-beta receptor,Tumor necrosis factor

Mouse HEK293 Cells
It is a single-pass type I membrane protein and contains 4 TNFR-Cys repeats. The protein is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein is the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. It promotes apoptosis via TRAF3 and TRAF5 and may play a role in the development of lymphoid organs...
TMPY-05176 AMH Protein, Human, Recombinant (His)

MIS,anti-Mullerian hormone,MIF

Human HEK293 Cells
Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and the FSH-dependent development of follicles. BMP15 up-regulates the transcription of AMH and that the inhibition of p38 MAPK decreases the BMP15-induced expression of AMH and SOX9, suggesting that BMP15 up-regulates the expression of AMH via the p38 MAPK signaling pathway, and thi...
TMPJ-01011 FGF-9 Protein, Mouse, Recombinant (His)

heparin-binding growth factor-9,GAF,HBGF-9,Glia-act...

Mouse E. coli
Fibroblast growth factor-9 (FGF-9) is an approximately 26 kDa secreted glycoprotein of the FGF family. Secreted mouse FGF-9 lacks the N-terminal 1-3 aa and shares >98% sequence identity with rat, human, equine, porcine and bovine FGF-9. FGF-9 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. In the mouse embryo the location and timing of FGF-9 expression affects development of the skeleton, cerebellum, lungs, heart, v...
TMPY-02014 Coagulation factor VII/F7 Protein, Human, Recombinant (His)

coagulation factor VII (serum prothrombin conversio...

Human HEK293 Cells
Coagulation factor VII, also known as Serum prothrombin conversion accelerator, Factor VII, F7 and FVII, is a member of the peptidase S1 family. Factor VII is one of the central proteins in the coagulation cascade. It is an enzyme of the serine protease class, and Factor VII (FVII) deficiency is the most frequent among rare congenital bleeding disorders. Factor VII contains two EGF-like domains, one Gla (gamma-carboxy-glutamate) domain and one peptidase S1 domain. The main role of factor VII is ...
TMPH-03211 TFPI Protein, Rabbit, Recombinant (His)

Rabbit HEK293 Cells
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. TFPI Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with N-10xHis tag. The predicted molecular weight is 35.4 kDa and the accession number is P19761.
TMPH-03210 TFPI Protein, Rabbit, Recombinant (E. coli, His)

Rabbit E. coli
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. TFPI Protein, Rabbit, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.8 kDa and the accession number is P19761.
TMPJ-00650 FIBP Protein, Human, Recombinant

FIBP,aFGF Intracellular-Binding Protein,FGF-1 Intracellular-...

Human E. coli
Acidic Fibroblast Growth Factor Intracellular-Binding Protein (FIBP) is highly expressed in the heart, skeletal muscle, and pancreas. Acidic Fibroblast Growth Factor is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FIBP is an intracellular protein that binds ...
TMPK-00570 CD46 Protein, Canine, Recombinant (His)

CD46,AHUS2,TRA2.10,LOC609365,TLX,MCP,MIC10,Membrane cofa...

Canine HEK293 Cells
CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated 'self-attack'. CD46 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells w...
TMPK-00532 CD46 Protein, Cynomolgus, Recombinant (His)

CD46,MCP,TLX,MIC10,AHUS2,TRA2.10

Cynomolgus HEK293 Cells
CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated 'self-attack'. CD46 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cel...
TMPJ-01121 MORF4L2 Protein, Human, Recombinant (His)

MORF4L2,Transcription Factor-Like Protein MRGX,Prot...

Human E. coli
Mortality Factor 4-Like Protein 2 (MORF4L2) is a member of the mortality factor (MORF) family. MORF4L2 localizes in the nucleus, possessing a protein kinase C phosphorylation site and a tyrosine phosphorylation site. MORF4L2 interacts with the Rb tumor suppressor and it has histone deacetylase activity which can either repress or promote the activity of the B-Myb promoter depending on the tissue. In addition, MORF4L2 is involved in cell growth, regulation, and senescence.
TMPK-00766 KLKB1 Protein, Human, Recombinant (His)

PKK,Kininogenin,KLK3,KLKB1,Fletcher factor,Plasma k...

Human HEK293 Cells
Plasma kallikrein, also known as Fletcher factor or kallikrein B1 (KLKB1), is a serine endopeptidase, like its homologs tissue kallikrein and kallikrein-related peptidases (KLKs). Its physiological role is to catalyze the release of kinins and other vasoactive peptides. KLKB1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 70.3 kDa and the accession number is P03952.
TMPH-03151 Gingipain R1 Protein, Porphyromonas gingivalis, Recombinant (His)

Porphyromonas gingivalis P. pastoris (Yeast)
Thiol protease. Acts synergistically with RgpB to catalyze the maturation of fimbrial subunits, such as FimA. Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms (Probable). Gingipain R1 Protein, Porphyromonas gingivalis, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 56.0 kDa and the accession number is P28784.
TMPK-00525 KLKB1 Protein, Cynomolgus, Recombinant (His)

KLK3,Plasma kallikrein,KLKB1,PKK,Kininogenin,Fletcher fa...

Cynomolgus HEK293 Cells
Plasma kallikrein, also known as Fletcher factor or kallikrein B1 (KLKB1), is a serine endopeptidase, like its homologs tissue kallikrein and kallikrein-related peptidases (KLKs). Its physiological role is to catalyze the release of kinins and other vasoactive peptides. KLKB1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 70.19 kDa and the accession number is A0A2K5VTJ9.
TMPK-00857 KLKB1 Protein, Mouse, Recombinant (His)

Kininogenin,KLK3,Fletcher factor,Plasma kallikrein,...

Mouse HEK293 Cells
Plasma kallikrein, also known as Fletcher factor or kallikrein B1 (KLKB1), is a serine endopeptidase, like its homologs tissue kallikrein and kallikrein-related peptidases (KLKs). Its physiological role is to catalyze the release of kinins and other vasoactive peptides. KLKB1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 70.3 kDa and the accession number is P26262.
TMPH-02832 Serpin A5 Protein, Mouse, Recombinant (His)

Mouse Baculovirus Insect Cells
Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extravascular proteolytic activities. Plays hemostatic roles in the blood plasma. Acts as a procoagulant and proinflammatory factor by inhibiting the anticoagulant activated protein C factor as well as the generation of activated protein C factor by the thrombin/thrombomodulin comple...
TMPJ-00274 LTBR Protein, Human, Recombinant (His)

TNFCR,Tumor Necrosis Factor Receptor Superfamily Me...

Human HEK293 Cells
Tumor necrosis factor receptor superfamily member 3, also known as Lymphotoxin-beta receptor,Tumor necrosis factor C receptor,Tumor necrosis factor receptor 2-related protein,Tumor necrosis factor receptor type III,LTBR,TNFCR, TNFR3 and TNFRSF3, is a member of the tumor necrosis factor (TNF) family of receptors. LTBR is a single-pass type I membrane protein and contains four TNFR-Cys repeats. It is expressed on the surface of most cell types, but not on T and B lymphocytes. LTBR and its ligand p...
TMPK-00024 Midkine Protein, Human, Recombinant (His & Avi), Biotinylated

MK1,MK,MDK,NEGF2,MKARAP,MEK,ARAP

Human E. coli
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Hu...
TMPK-00023 Midkine Protein, Human, Recombinant (His & Avi)

MDK,MEK,MK1,MKARAP,ARAP,MK,NEGF2

Human E. coli
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Hu...
TMPJ-00073 FGF-7/KGF Protein, Human, Recombinant

Fibroblast growth factor 7,成纤维细胞生长因子,FGF-7,Heparin-...

Human E. coli
Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in...
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重组蛋白

Tissue Factor Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-05094
Species: Cynomolgus
Expression System: HEK293 Cells
Tissue Factor Protein, Human, Recombinant (His)
Cat.No: TMPY-02530
Species: Human
Expression System: HEK293 Cells
Tissue Factor Protein, Rabbit, Recombinant (His)
Cat.No: TMPY-02318
Species: Rabbit
Expression System: HEK293 Cells
Tissue Factor Protein, Rat, Recombinant (His)
Cat.No: TMPY-03209
Species: Rat
Expression System: HEK293 Cells
Tissue Factor Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02537
Species: Human
Expression System: HEK293 Cells
Coagulation Factor III/Tissue Factor Protein, Canine, Recombinant (His)
Cat.No: TMPK-00993
Species: Canine
Expression System: HEK293 Cells
Tissue Factor Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01325
Species: Mouse
Expression System: HEK293 Cells
Tissue Factor Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-06957
Species: Human
Expression System: HEK293 Cells
Tissue Factor Protein, Human, Recombinant (aa 1-295, His)
Cat.No: TMPY-05083
Species: Human
Expression System: Baculovirus Insect Cells
TFPI Protein, Human, Recombinant (His)
Cat.No: TMPY-01030
Species: Human
Expression System: HEK293 Cells
CTGF/CCN2 Protein, Human, Recombinant (HEK293, His)
Cat.No: TMPJ-01163
Species: Human
Expression System: HEK293 Cells
TFPI2 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02859
Species: Mouse
Expression System: HEK293 Cells
TFPI2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02329
Species: Mouse
Expression System: HEK293 Cells
TFPI2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01004
Species: Human
Expression System: HEK293 Cells
TFPI Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05179
Species: Human
Expression System: HEK293 Cells
TFPI Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00928
Species: Mouse
Expression System: HEK293 Cells
CTGF/CCN2 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-01162
Species: Human
Expression System: HEK293 Cells
CTGF/CCN2 Protein, Human, Recombinant
Cat.No: TMPJ-01161
Species: Human
Expression System: HEK293 Cells
CTGF/CCN2 Protein, Mouse, Recombinant (GST)
Cat.No: TMPH-02568
Species: Mouse
Expression System: E. coli
CTGF/CCN2 Protein, Human, Recombinant (His)
Cat.No: TMPH-01069
Species: Human
Expression System: E. coli
Resistin Protein, Human, Recombinant (His)
Cat.No: TMPJ-00014
Species: Human
Expression System: E. coli
FGF-9 Protein, Human, Recombinant
Cat.No: TMPJ-00090
Species: Human
Expression System: E. coli
TGF alpha Protein, Human, Recombinant
Cat.No: TMPY-03958
Species: Human
Expression System: E. coli
Von Willebrand Factor/vWF Protein, Human, Recombinant (His)
Cat.No: TMPY-01075
Species: Human
Expression System: CHO Cells
FGF-16 Protein, Human, Cynomolgus, Recombinant
Cat.No: TMPY-00117
Species: Human,Cynomolgus
Expression System: Baculovirus Insect Cells
FGF-6 Protein, Human, Recombinant
Cat.No: TMPY-03382
Species: Human
Expression System: E. coli
FGF-2 Protein, Rat, Recombinant
Cat.No: TMPJ-00842
Species: Rat
Expression System: E. coli
FGF-17 Protein, Human, Recombinant
Cat.No: TMPY-03104
Species: Human
Expression System: E. coli
Coagulation factor X/F10 Protein, Human, Recombinant (His)
Cat.No: TMPY-01101
Species: Human
Expression System: Baculovirus Insect Cells
FGF-10 Protein, Human, Recombinant
Cat.No: TMPY-01061
Species: Human
Expression System: E. coli
FGF-19 Protein, Human, Recombinant
Cat.No: TMPY-02907
Species: Human
Expression System: E. coli
LTBR Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00994
Species: Mouse
Expression System: HEK293 Cells
AMH Protein, Human, Recombinant (His)
Cat.No: TMPY-05176
Species: Human
Expression System: HEK293 Cells
FGF-9 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01011
Species: Mouse
Expression System: E. coli
Coagulation factor VII/F7 Protein, Human, Recombinant (His)
Cat.No: TMPY-02014
Species: Human
Expression System: HEK293 Cells
TFPI Protein, Rabbit, Recombinant (His)
Cat.No: TMPH-03211
Species: Rabbit
Expression System: HEK293 Cells
TFPI Protein, Rabbit, Recombinant (E. coli, His)
Cat.No: TMPH-03210
Species: Rabbit
Expression System: E. coli
FIBP Protein, Human, Recombinant
Cat.No: TMPJ-00650
Species: Human
Expression System: E. coli
CD46 Protein, Canine, Recombinant (His)
Cat.No: TMPK-00570
Species: Canine
Expression System: HEK293 Cells
CD46 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00532
Species: Cynomolgus
Expression System: HEK293 Cells
MORF4L2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01121
Species: Human
Expression System: E. coli
KLKB1 Protein, Human, Recombinant (His)
Cat.No: TMPK-00766
Species: Human
Expression System: HEK293 Cells
Gingipain R1 Protein, Porphyromonas gingivalis, Recombinant (His)
Cat.No: TMPH-03151
Species: Porphyromonas gingivalis
Expression System: P. pastoris (Yeast)
KLKB1 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00525
Species: Cynomolgus
Expression System: HEK293 Cells
KLKB1 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00857
Species: Mouse
Expression System: HEK293 Cells
Serpin A5 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02832
Species: Mouse
Expression System: Baculovirus Insect Cells
LTBR Protein, Human, Recombinant (His)
Cat.No: TMPJ-00274
Species: Human
Expression System: HEK293 Cells
Midkine Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00024
Species: Human
Expression System: E. coli
Midkine Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00023
Species: Human
Expression System: E. coli
FGF-7/KGF Protein, Human, Recombinant
Cat.No: TMPJ-00073
Species: Human
Expression System: E. coli
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